Matt Short comes into the 13-man squad to replace Chris Tremain.
The Renegades are on top of the Big Bash ladder after a six wicket win over Melbourne Stars.
Short, a 22 year old all-rounder, played for the Renegades last season and represented Victoria in the JLT One Day Cup last October.
Perth Scorchers v Melbourne Renegades
Monday January 8
WACA, 6:25pm (AWST) / 9:25pm (AEDT)
BBL Squad v Perth Scorchers
Aaron Finch (Captain)