Three changes have been made to the final XI, with James Seymour, James Pattinson and Zak Evans coming into the team.
Seymour was injected into the team as an X-factor sub in Monday night’s win against the Melbourne Stars.
Fast bowler James Pattinson returns to availability after a negative PCR test, while fellow quick Zak Evans will make his first appearance for BBL|11.
Nic Maddinson (C)
Two players have returned positive tests for COVID-19 and are unavailable for selection.
England fast bowler Reece Topley signed off on his stint with the Renegades on Monday night ahead of T20 international duties.
Channel 7, Fox Cricket, Kayo and SEN 1116 will broadcast the game live.
Melbourne Renegades v Brisbane Heat
Thursday 6 January
GMHBA Stadium, Geelong
*To view the full Melbourne Renegades' fixture for BBL|11, click here.
*Tickets to KFC BBL|11 matches are on sale now.