Cameron White returns from Australian duties and will captain the side.
Fast bowler Joe Mennie has also been included in the squad.
Kane Richardson will miss the BBL finals series after his call-up to the Australian T20 squad while Brad Hogg was left out.
Adelaide Strikers v Melbourne Renegades
Friday February 2, 7:40pm (AEDT) / 7:10pm (ACDT)
Melbourne Renegades Squad v Strikers
Cameron White (captain)
Travis Head (c)
Harry Nielsen (wk)