Tom Cooper, Cameron White, Jack Wildermuth, Chris Tremain and Brad Hogg impressed in the first leg of the double header.
After White won the toss (regular captain Aaron Finch was rested), the Renegades slumped to 3-14 inside the first four overs as Marcus Harris, Tim Ludeman and Brad Hodge fell cheaply.
Cooper (68 off 46 balls, four 4s, four 6s) led the revival. He and White (26 off 27 balls) combined for a 70-run partnership to rebuild the innings.
The shift in momentum continued when Cooper was joined by ex-Heat all-rounder Jack Wildermuth (47 off 25 balls, four 4s, two 6s). The Queenslander took to his state teammates, dispatching the ball to all parts of the expansive John Blank Oval.
The Renegades finished on 6-169 and made a bright start with the ball restricting the Heat to 2-43 from the first eight overs.
But the big hitting of Ben Cutting (50 off 29 balls) put the home side in striking distance before the Renegades steadied to close out the win.
Tremain (2-33 off four overs), Hogg (1-19 off four overs) and Kane Richardson (2-30 off three overs) showed positive signs with the ball.
The Renegades and the Heat meet in another practice match on Saturday.