The Renegades have defeated the Heat by one run at a sold-out Gabba to keep their season alive.
The Heat needed 18 off the final over, but the equation rapidly became five off four when Nathan Rimmington bowled a wide before Joe Burns sent his next two balls flying into the stands.
Burns holed out next ball, but it was four off three required when Rimmington bowled another wide.
A run out followed next ball, before another Rimmington wide left the Heat needing three off two with just one wicket in hand.
A dot ball followed and just when you thought the finish couldn't get any better, Rimmington's final ball produced yet another wide, but it mattered not as Mitch Swepson took off for a panicked single, only to be run out.
The final over: 1wd 6 6 W 1wd W 1wd 0 W(1wd)
Earlier, half-centuries from Renegades openers Aaron Finch and Marcus Harris helped their side get off to a flying start.
Needing victory at the Gabba to stay in finals contention, the Renegades began with clear intent after losing the toss.
Finch and Harris combined for a damaging first-wicket stand of 106 off just 55 balls, punishing some loose bowling from Brisbane's pace attack.
It was the sixth-highest partnership in Renegades franchise history, while their tally of 75 from the six-over powerplay was the second best of the tournament.
The openers smacked six boundaries apiece, with Finch - who was dropped from Australia's ODI squad earlier this month - clearing the fence four times and Harris once.
Ben Cutting eventually broke the partnership with his first delivery of the match, Harris edging to Joe Burns at point to start the ninth over.
Finch was caught on the mid-wicket boundary by Marnus Labuschagne, mistiming a swipe at a Mark Steketee slow ball to leave Melbourne at 2-137 after 13 overs.
Their run rate slowed dramatically after that, with Cameron White's run-a-ball 24 failing to carry the momentum.
But two sixes and a four in the final over from Callum Ferguson (31no) helped pad out the Renegades' innings, which finished at 5-199.
Over by over
1: Renegades 0/12, Heat 0/14
2: Renegades 0/26, Heat 1/36
3: Renegades 0/38, Heat 1/49
4: Renegades 0/50, Heat 1/63
5: Renegades 0/60, Heat 1/84
6: Renegades 0/75, Heat 2/85
7: Renegades 0/80, Heat 2/92
8: Renegades 0/101, Heat 2/98
9: Renegades 0/106, Heat 2/101
10: Renegades 1/114, Heat 2/107
11: Renegades 1/120, Heat 2/119
12: Renegades 1/129, Heat 3/126
13: Renegades 1/136, Heat 4/129
14: Renegades 2/142, Heat 4/137
15: Renegades 2/155, Heat 4/147
16: Renegades 3/161, Heat 4/161
17: Renegades 4/165, Heat 4/166
18: Renegades 4/172, Heat 5/174
19: Renegades 5/179, Heat 7/182
20: Renegades 5/199, Heat 198